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Specificity of rabbit pulmonary cytochrome P-450 isozymes in the activation of several aromatic amines and aflatoxin B1.

作者信息

Robertson L G, Philpot R M, Zeiger E, Wolf C R

出版信息

Mol Pharmacol. 1981 Nov;20(3):662-8.

PMID:6799775
Abstract
摘要

相似文献

1
Specificity of rabbit pulmonary cytochrome P-450 isozymes in the activation of several aromatic amines and aflatoxin B1.兔肺细胞色素P-450同工酶在几种芳香胺和黄曲霉毒素B1激活中的特异性。
Mol Pharmacol. 1981 Nov;20(3):662-8.
2
Specificity of rat liver cytochrome P-450 isozymes in the mutagenic activation of benzo[a]pyrene, aromatic amines and aflatoxin B1.
Carcinogenesis. 1983;4(1):93-6. doi: 10.1093/carcin/4.1.93.
3
Modulation of aflatoxin B1 biotransformation in rabbit pulmonary and hepatic microsomes.黄曲霉毒素B1在兔肺和肝微粒体中的生物转化调控
Toxicology. 1992 Aug;74(1):19-32. doi: 10.1016/0300-483x(92)90040-l.
4
The relationship between increases in the hepatic content of cytochrome P-450, form 5, and in the metabolism of aromatic amines to mutagenic products following treatment of rabbits with phenobarbital.用苯巴比妥处理兔子后，细胞色素P - 450 5型肝脏含量的增加与芳香胺代谢为诱变产物之间的关系。
Mol Pharmacol. 1983 Jul;24(1):156-62.
5
Metabolism and activation of aflatoxin B1 by reconstituted cytochrome P-450 system of rat liver.黄曲霉毒素B1在大鼠肝脏重组细胞色素P-450系统中的代谢与激活
Cancer Res. 1982 Mar;42(3):1120-4.
6
Contributions of two inducible forms of cytochrome P-450 in rat liver microsomes to the metabolic activation of various chemical carcinogens.
Cancer Res. 1983 Feb;43(2):819-23.
7
Mutagenic activation of aflatoxin B1 by several forms of purified cytochrome P-450.黄曲霉毒素B1经多种纯化细胞色素P-450形式的诱变激活作用。
Mutat Res. 1986 Jun;174(2):85-8. doi: 10.1016/0165-7992(86)90095-3.
8
Comparative study on the metabolism and activation of aflatoxin B1 in nuclet, microsomes and reconstituted P-450 system of rat liver.
Dev Toxicol Environ Sci. 1980;8:279-82.
9
Oltipraz-mediated changes in aflatoxin B(1) biotransformation in rat liver: implications for human chemointervention.奥替普拉介导的大鼠肝脏中黄曲霉毒素B（1）生物转化的变化：对人类化学干预的意义。
Cancer Res. 1996 May 15;56(10):2306-13.
10
Role of human microsomal and human complementary DNA-expressed cytochromes P4501A2 and P4503A4 in the bioactivation of aflatoxin B1.人微粒体及人互补DNA表达的细胞色素P4501A2和P4503A4在黄曲霉毒素B1生物活化中的作用
Cancer Res. 1994 Jan 1;54(1):101-8.

引用本文的文献

1
Noncovalent interactions dominate dynamic heme distortion in cytochrome P450 4B1.非共价相互作用主导细胞色素 P450 4B1 中血红素的动态变形。
J Biol Chem. 2018 Jul 20;293(29):11433-11446. doi: 10.1074/jbc.RA118.004044. Epub 2018 Jun 1.
2
Role of cytochrome P-450 and related enzymes in the pulmonary metabolism of xenobiotics.细胞色素P-450及相关酶在外源化学物肺代谢中的作用。
Environ Health Perspect. 1984 Apr;55:359-67. doi: 10.1289/ehp.8455359.
3
Metabolism of 2-acetylaminofluorene by Clara cells, type II cells and alveolar macrophages isolated from rabbit lung, and use of a new chamber incubation mutagenicity test system.
兔肺分离的克拉拉细胞、II型细胞和肺泡巨噬细胞对2-乙酰氨基芴的代谢，以及一种新型小室培养诱变性测试系统的应用。
Cell Biol Toxicol. 1985 Jun;1(3):109-22. doi: 10.1007/BF00120158.
4
3-Methylcholanthrene-induced ethoxyresorufin O-deethylase activity in alveolar type II cells of rabbit lung.
Arch Toxicol. 1986 May;59(1):1-3. doi: 10.1007/BF00263947.
5
Evidence for involvement of multiple forms of cytochrome P-450 in aflatoxin B1 metabolism in human liver.多种细胞色素P-450参与人肝脏中黄曲霉毒素B1代谢的证据。
Proc Natl Acad Sci U S A. 1990 Nov;87(21):8306-10. doi: 10.1073/pnas.87.21.8306.