Frontera Izquierdo P, Cabezuelo Huerta G, Carles Genovés C
An Esp Pediatr. 1981 Sep;15(3):278-83.
The role of antidiuretic hormone in maintaining normal water balance is review. The diagnosis of inappropriate secretion of antidiuretic hormone is done when a patient presents hyponatremia with no evidence of volume depletion, urine osmolality that is inappropriately high for serum tonicity, and absence of intrinsic renal or adrenal disease. Among the various possible etiology, the most frequent corresponds to disorders of the central nervous system, particularly bacterial meningitis. The various methods of treatment, fluid restriction, Hantman method and lithium salts are discussed.
本文综述了抗利尿激素在维持正常水平衡中的作用。当患者出现低钠血症且无容量耗竭证据、尿渗透压相对于血清张力过高且无内在肾脏或肾上腺疾病时，可诊断为抗利尿激素分泌不当。在各种可能的病因中，最常见的是中枢神经系统疾病，尤其是细菌性脑膜炎。文中还讨论了多种治疗方法，包括液体限制、汉特曼方法和锂盐。
