Yinon U
Exp Brain Res. 1978 Jun 19;32(2):275-85. doi: 10.1007/BF00239732.
During the first 2 weeks following unilateral severance of the 6 extraocular eye muscles in adult cats, the operated eye is partially immobile as shown by electrooculographic (EOG) recordings of horizontal eye movements. Although the motility of the operated eye improves with time (mainly in terms of amplitude but also with regard to direction and frequency of movements), it does not reach (up to 2 months) the level of the normal eye. Unit recording was done in visual cortex area 17 of these cats while paralyzed, either immediately (acute group, 5 cats), or 3-60 days (chronic group, 6 cats) following the operation. The number of visually inactive cells was slightly higher in the operated cats (13.8%) than in normal cats (8.3%), but the number of nonoriented cells or cells with disorganized receptive fields was similar in both groups of cats. The proportion of binocularly activated cells in the operated cats, especially in the chronic group (greater than 10 days after the operation, 71.2% of 153 cells), was similar to that of the normal control cats (72.8% of 236 cells). No ocular dominance shift was found when either the operated eye was compared to the normal one or the ipsilateral eye to the contralateral one. It was concluded that distortion of afferent proprioceptive input from the extraocular eye muscles to visual centers has no effect on binocularity of cortical neurons in adult cats.
在成年猫单侧切断6条眼外肌后的前2周内，如通过水平眼动的眼电图（EOG）记录所示，手术眼部分无法活动。尽管手术眼的运动能力随时间有所改善（主要体现在幅度方面，在运动方向和频率上也有改善），但在2个月内仍未达到正常眼的水平。在这些猫处于瘫痪状态时，对其视觉皮层17区进行单细胞记录，记录时间为手术刚结束后（急性组，5只猫）或术后3 - 60天（慢性组，6只猫）。手术猫中视觉无反应细胞的数量（13.8%）略高于正常猫（8.3%），但两组猫中非定向细胞或感受野紊乱细胞的数量相似。手术猫中双眼激活细胞的比例，尤其是慢性组（术后超过10天，153个细胞中的71.2%），与正常对照猫（236个细胞中的72.8%）相似。当将手术眼与正常眼进行比较，或将同侧眼与对侧眼进行比较时，未发现眼优势性转移。研究得出结论，从眼外肌到视觉中枢的传入本体感觉输入的扭曲对成年猫皮层神经元的双眼性没有影响。
