皮肤癌的胶原结合糖蛋白。

Collagen-bound glycoprotein of Guerin epithelioma.

作者信息

Romański I, Bańkowski E, Rzeczycki W

出版信息

Exp Pathol (Jena). 1978;15(2):116-23. doi: 10.1016/s0014-4908(78)80076-3.

Abstract

The polymeric collagen of Guerin epithelioma is strongly bound to a large amount of noncollagenous substance. Almost full dissociation of this complex was achieved by heating in 7 Murea, at 100 degrees C for 4 hours. The collagen bound substance was identified as an acidic glycoprotein containing glucose, galactose, glucosamine, galactosamine and M-acetylneuraminic acid. Heterogeneity of this substance in regard to molecular weight was found.

摘要

盖林上皮瘤的聚合胶原与大量非胶原物质紧密结合。通过在7M尿素中于100℃加热4小时，几乎完全实现了这种复合物的解离。与胶原结合的物质被鉴定为一种含有葡萄糖、半乳糖、氨基葡萄糖、半乳糖胺和N-乙酰神经氨酸的酸性糖蛋白。发现该物质在分子量方面具有异质性。