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磁场对大鼠某些体液参数及热耐受能力的影响。

The influence of magnetic fields on some humoral parameters and on resistance to hyperthermia in rats.

作者信息

Groza P, Nicolescu E, Lazăr I, Cananău S A, Bubuianu E, Daneliuc E, Munteanu A, Lungu D, Ionescu S, Netea F, Anca F

出版信息

Physiologie. 1982 Jan-Mar;19(1):15-24.

PMID:6801711
Abstract

The influence of magnetic fields of moderate intensities (50 and 120 Oe) was studied in rats after single or repeated exposures with or without a rise in environmental temperature. The following parameters were investigated: the number of erythrocytes and leucocytes, the percentage of different varieties of leucocytes, serum Na+ and K+, plasma corticosterone, ascorbic acid in adrenals, blood catecholamines, plasma fibrinolytic activity, plasma antidiuretic hormone. The resistance to hyperthermia was tested after single exposures to magnetic fields and the survival time was measured. The only significant change recorded in the number of blood cells was a leucopenia after single exposures to 50 Oe for 4 hrs. The parameters indicating the activity of the adrenal cortex were not altered significantly. A moderate rise in blood noradrenaline suggested a possible mild stimulation of the adrenergic system. The plasma fibrinolytic activity was significantly stimulated after single exposures, but no change in fibrinolysis could be recorded after repeated exposures to magnetic fields. Changes observed in plasma ADH were not conclusive. The resistance of animals to hyperthermia - as a general test of reactivity - showed minimal changes in the survival time, loss of weight, and rectal temperature in animals exposed to hyperthermia (40 degrees C) under the influence of the magnetic fields.

摘要

研究了中等强度(50和120奥斯特)磁场在有或无环境温度升高的情况下单次或重复暴露于大鼠后的影响。研究了以下参数:红细胞和白细胞数量、不同种类白细胞的百分比、血清钠和钾、血浆皮质酮、肾上腺中的抗坏血酸、血儿茶酚胺、血浆纤维蛋白溶解活性、血浆抗利尿激素。在单次暴露于磁场后测试了对热疗的抵抗力并测量了存活时间。在血细胞数量方面记录到的唯一显著变化是单次暴露于50奥斯特4小时后出现白细胞减少。表明肾上腺皮质活性的参数没有明显改变。血去甲肾上腺素适度升高表明可能对肾上腺素能系统有轻度刺激。单次暴露后血浆纤维蛋白溶解活性受到显著刺激,但重复暴露于磁场后未记录到纤维蛋白溶解的变化。观察到的血浆抗利尿激素变化尚无定论。作为反应性的一般测试,动物对热疗的抵抗力在磁场影响下暴露于热疗(40摄氏度)的动物的存活时间、体重减轻和直肠温度方面显示出最小的变化。

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