Makarov M A, Cherkasskiĭ L A
Vopr Onkol. 1982;28(3):77-81.
The effects of different periods of hypokinesia on the development of 7.12-dimethyl-benzoanthracene-induced osteosarcoma of shinbone were studied in 148 rabbits. The time of induction was found to decrease considerably - from 197.6 to 113.9 days. This may be attributed to hypokinesia's constituting a stress, which involves release of adrenocortical hormones, atrophy of the thymus and reduced cellular immunological vigor.
在148只家兔身上研究了不同时期运动功能减退对7,12-二甲基苯并蒽诱导的胫骨骨肉瘤发展的影响。发现诱导时间显著缩短——从197.6天缩短至113.9天。这可能归因于运动功能减退构成一种应激，涉及肾上腺皮质激素的释放、胸腺萎缩和细胞免疫活力降低。
