Palva T, Raunio V
Acta Otolaryngol. 1982;93(1-6):201-3. doi: 10.3109/00016488209130872.
White rabbits were immunized with pooled and concentrated cerebro-spinal fluid (CSF) and with tumour homogenate concentrate from specimens taken from five patients with acoustic neurinoma. The absorbed anti-CSF-antitumour antiserum was tested with the micro-immunodiffusion test against normal human serum (NHS), CSF, perilymph and CSF from tumour patients and tumour homogenate. NHS showed no precipitates in any of the tests. One protein band was observed in all the other four reactants. Tumour tissue and perilymph had two proteins in common. Diffusion from the CSF space into the perilymph can thus occur via both the cochlear aqueduct and the internal acoustic meatus.
用汇集浓缩的脑脊液（CSF）以及取自5例听神经瘤患者标本的肿瘤匀浆浓缩物对白兔进行免疫。用微量免疫扩散试验，以吸收后的抗脑脊液-抗肿瘤抗血清检测正常人血清（NHS）、脑脊液、外淋巴以及肿瘤患者的脑脊液和肿瘤匀浆。在所有检测中，NHS均未出现沉淀。在其他四种反应物中均观察到一条蛋白带。肿瘤组织和外淋巴有两种共同的蛋白。因此，脑脊液可通过蜗水管和内耳道从脑脊液间隙扩散至外淋巴。
