Yangco B G, Germain B F, Deresinski S C
Am J Med Sci. 1982 Mar-Apr;283(2):94-8. doi: 10.1097/00000441-198203000-00008.
Gas gangrene is a rare infectious disease syndrome complicating medico-surgical procedures. We describe a case of gas gangrene secondary to intra-articular steroid injection. Clostridia species and Escherichia coli were the etiologic organisms in this case. The presence of underlying diseases such as diabetes mellitus, hepatic insufficiency, and metabolic acidosis could have contributed to the fatal outcome of this patient. A high index of suspicion, early diagnosis, and appropriate treatment may improve the prognosis in gas gangrene. Although uncommon, infection is a significant complication of intra-articular steroid administration. Thus, meticulous aseptic technique should always be observed in the performance of this procedure.
气性坏疽是一种罕见的感染性疾病综合征，常使医疗外科手术复杂化。我们描述了一例因关节内注射类固醇继发气性坏疽的病例。梭状芽孢杆菌属和大肠杆菌是该病例的致病微生物。糖尿病、肝功能不全和代谢性酸中毒等基础疾病的存在可能是导致该患者死亡的原因。高度的怀疑指数、早期诊断和适当的治疗可能会改善气性坏疽的预后。虽然罕见，但感染是关节内注射类固醇的一种重要并发症。因此，在进行该操作时应始终严格遵守无菌技术。
