雄性恒河猴下丘脑-腺垂体功能。一种灵长类动物模型。

Hypothalamic-adenohypophyseal function in male rhesus monkeys. A primate model.

作者信息

Chrousos G P, Poplack D, Kostolich M, Wiede C, Oliff A, Brown T, Bercu B B

出版信息

J Med Primatol. 1981;10(2-3):61-71. doi: 10.1159/000460056.

Abstract

The secretion of six anterior pituitary hormones in both the basal state and after stimulation or suppression in nine young adults male rhesus monkeys (Macaca mulatta) was studied. Growth hormone (GH), prolactin, thyroid-stimulating hormone (TSH), luteinizing hormone (LH), and follicle-stimulating hormone (FSH) secretion were evaluated. Adrenocorticotropin hormone (ACTH) secretion was studied indirectly by measuring plasma cortisol levels. The tests were performed in combination and in sequence over a 7-hour period. Thus, multiple functions of the hypothalamic-hypophyseal axis can be studied quickly utilizing small quantities of blood.

摘要

对9只成年雄性恒河猴（猕猴）在基础状态下以及刺激或抑制后六种垂体前叶激素的分泌情况进行了研究。评估了生长激素（GH）、催乳素、促甲状腺激素（TSH）、黄体生成素（LH）和促卵泡激素（FSH）的分泌。通过测量血浆皮质醇水平间接研究促肾上腺皮质激素（ACTH）的分泌。这些测试在7小时内组合并按顺序进行。因此，利用少量血液就能快速研究下丘脑 - 垂体轴的多种功能。