Carile L, Laquaglia G A, Martone P, Marchionni F, Di Falco C
Minerva Med. 1982 Apr 2;73(14):821-7.
The authors realized a retrospective clinical-statistical study about 121 cases of acute myocardial infarction (AMI), treated in the Department of general medicine with a pharmacological association of Lysine acetylsalicylate--Erythrityl tetranitrate--Papaverine hydrochloride, with the purpose of obtaining a vasodilatation on coronary arteries and a platelet antiaggregation, in the light of the new etiopathogenetic views about the prolonged coronary spasm and the platelet aggregation, in some cases of myocardial infarction with or without thrombosis. Obtained data are very optimistic about incidence of left ventricular insufficiency and (of) thromboembolisms, to they augur the sistematic adoption of this treatment of AMI, especially as to the early antiaggregation therapy.
作者针对121例急性心肌梗死(AMI)患者进行了一项回顾性临床统计研究。这些患者在内科接受了赖氨酸乙酰水杨酸 - 四硝酸赤藓醇 - 盐酸罂粟碱的联合药物治疗,目的是根据关于延长冠状动脉痉挛和血小板聚集的新病因学观点,在一些伴有或不伴有血栓形成的心肌梗死病例中实现冠状动脉血管舒张和血小板抗聚集。所获得的数据在左心室功能不全和血栓栓塞发生率方面非常乐观,这预示着该AMI治疗方法将被系统采用,特别是在早期抗聚集治疗方面。