Rütti W
Schweiz Med Wochenschr. 1982 Mar 27;112(13):434-41.
Case-histories and EEG-findings have been analyzed in 42 patients of whom 34 were still suffering from petit-mal seizures after the age of 25 years, while the remaining 8 showed subclinical 3 c/sec spike-waves in the interval between grand-mal attacks. Out of these 42 patients, 20 had "primary generalized" i.e. "idiopathic" epilepsy, 19 of the 20 having had it since childhood or adolescence. Only in one case (5%) did there seem to be a later onset. In 3 of the remaining 22 patients (14%) suffering from "secondary generalized" i.e. "symptomatic" epilepsy, the age of onset was between 20 and 22 years. 24% of all patients exhibited petit-mal states in the course of their illness. In the female population petit-mal states were found in 33% and in the male population only in 11%. In none of 8 patients who suffered from grand-mal seizures alone and had subclinical 3 c/sec spike-waves did there appear to be any petit-mal seizures during an average observation time of 3 years.
对42例患者的病历和脑电图检查结果进行了分析。其中34例在25岁之后仍患有失神发作,其余8例在大发作的间歇期有亚临床3次/秒棘波。在这42例患者中,20例患有“原发性全身性”即“特发性”癫痫,其中19例自儿童期或青春期起就患有此病。仅1例(5%)似乎起病较晚。在其余22例患有“继发性全身性”即“症状性”癫痫的患者中,3例(14%)起病年龄在20至22岁之间。所有患者中有24%在病程中出现失神状态。女性患者中失神状态的发生率为33%,男性患者中仅为11%。在仅患有大发作且有亚临床3次/秒棘波的8例患者中,在平均3年的观察期内均未出现任何失神发作。