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结节病与膜性肾小球肾炎:一种显著关联。

Sarcoidosis and membranous glomerulonephritis: a significant association.

作者信息

Taylor R G, Fisher C, Hoffbrand B I

出版信息

Br Med J (Clin Res Ed). 1982 May 1;284(6325):1297-8. doi: 10.1136/bmj.284.6325.1297.

Abstract

Three patients were seen who had sarcoidosis associated with glomerulonephritis. Subsequent review of published reports of cases in which the two conditions occurred simultaneously showed a pattern of histological type of glomerulonephritis different from that seen in patients without associated disease. In sarcoidosis with glomerulonephritis there appeared to be a dearth of minimal-change disease and an excess of membranous glomerulonephritis compared with the prevalence that would be expected if the renal disease was merely a chance occurrence. These findings may provide evidence for an important relation between sarcoidosis and glomerulonephritis.

摘要

我们观察了3例患有结节病合并肾小球肾炎的患者。随后对已发表的两病同时发生的病例报告进行回顾,发现肾小球肾炎的组织学类型模式与无相关疾病患者所见不同。与肾病仅为偶然发生时预期的患病率相比,结节病合并肾小球肾炎时,微小病变性肾病似乎较少,而膜性肾小球肾炎较多。这些发现可能为结节病与肾小球肾炎之间的重要关系提供证据。

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