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人类皮肤中由C类纤维支配的伤害性感受器和温觉感受器。

Nociceptors and warm receptors innervated by C fibres in human skin.

作者信息

Hallin R G, Torebjörk H E, Wiesenfeld Z

出版信息

J Neurol Neurosurg Psychiatry. 1982 Apr;45(4):313-9. doi: 10.1136/jnnp.45.4.313.

Abstract

The properties of 125 C fibre units recorded from the peripheral nerves of conscious man were studied. On the basis of receptive field properties and responses to natural stimulation, 120 of the units were classified as polymodal C nociceptors. Five of the units were identified as specific C warm receptors. In contrast to the polymodal nociceptors, which often had comparatively large and complex receptive fields with several receptive maxima, receptive fields of the thermo-receptors consisted of one single spot. Polymodal nociceptors responded readily to moderately intense and noxious mechanical stimuli whereas the warm receptors produced inconsistent responses to even intense mechanical skin stimulation. Thermal stimulation in the innocuous range, perceived as warmth, optimally excited the thermoreceptors whereas the polymodal C nociceptors fired most intensely to noxious painful heat.

摘要

对从清醒人体外周神经记录到的125个C类纤维单位的特性进行了研究。根据感受野特性和对自然刺激的反应,其中120个单位被归类为多模式C类伤害感受器。5个单位被确定为特定的C类温觉感受器。与通常具有相对较大且复杂的感受野以及多个感受最大值的多模式伤害感受器不同,温觉感受器的感受野由单个点组成。多模式伤害感受器对中等强度和有害的机械刺激反应迅速,而温觉感受器即使对强烈的皮肤机械刺激也产生不一致的反应。无害范围内被感知为温暖的热刺激能最佳地激活温觉感受器,而多模式C类伤害感受器对有害的热痛刺激发放最为强烈。

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本文引用的文献

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The role of nonmyelinated fibres in signalling cooling of the skin.
J Physiol. 1960 Feb;150(2):266-83. doi: 10.1113/jphysiol.1960.sp006386.
2
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