[接种化学性斑疹伤寒疫苗者的抗毒免疫特性]
[Characteristics of the antitoxic immunity in persons inoculated with chemical typhus vaccine].
作者信息
Nikol'skaia V N, Imamaliev O G, Klimchuk N D
出版信息
Zh Mikrobiol Epidemiol Immunobiol. 1982 Mar(3):86-9.
The determination of toxin-neutralizing antibodies in the sera of persons immunized with chemical typhus vaccine revealed that immunization made both in a single injection and in two injections resulted in the development of antitoxic immunity practically in all vaccinees. No toxin-neutralizing antibodies could be detected 6 months after immunization. The booster injection made at that period resulted in the development of antitoxic immunity which was as pronounced as that developing after primary immunization. In the blood sera of the vaccines the titers of toxin-neutralizing antibodies practically did not differ from those of complement-fixing antibodies.
对接受化学性斑疹伤寒疫苗免疫的人群血清中的毒素中和抗体进行检测发现，无论是单次注射还是两次注射进行免疫，实际上所有接种者均产生了抗毒免疫力。免疫6个月后未检测到毒素中和抗体。在此期间进行的加强注射导致产生了与初次免疫后同样显著的抗毒免疫力。在接种者的血清中，毒素中和抗体的滴度与补体结合抗体的滴度实际上没有差异。
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