Henschke C I, Goldman H, Teele R L
AJR Am J Roentgenol. 1982 May;138(5):841-6. doi: 10.2214/ajr.138.5.841.
The clinical records of 28 patients seen in one institution during a recent 2 year period who, on sonography, had been identified as having a hyperechogenic (bright) liver were reviewed. Seven children were diagnosed as having metabolic diseases, four were malnourished, four were receiving hyperalimentation, 10 were receiving chemotherapy, and three were undiagnosed. The sonograms of all the patients and the histologic sections on those who had biopsies, were reevaluated in order to assess the sonographic pattern in greater detail, and these findings were correlated with fatty infiltration and fibrosis of the liver. The bright liver corresponded to the pathologic finding of fatty change. This sonographic finding in children is important, as further evaluation (hepatic biopsy with fat stain, enzymatic analyses, amino acid screens) can be suggested to identify underlying metabolic disorders in those not on therapy. Often the complications of metabolic diseases can be prevented or delayed by early diagnosis and appropriate therapy.
回顾了最近两年在一家机构就诊的28例患者的临床记录，这些患者在超声检查中被确定为肝脏回声增强（明亮）。7名儿童被诊断患有代谢性疾病，4名营养不良，4名接受肠外营养，10名接受化疗，3名未确诊。对所有患者的超声图像以及接受活检患者的组织学切片进行了重新评估，以便更详细地评估超声图像模式，并将这些发现与肝脏脂肪浸润和纤维化相关联。肝脏回声增强与脂肪变性的病理结果相对应。儿童的这种超声检查结果很重要，因为可以建议进一步评估（进行脂肪染色的肝活检、酶分析、氨基酸筛查），以识别未接受治疗患者潜在的代谢紊乱。通常，代谢性疾病的并发症可以通过早期诊断和适当治疗来预防或延缓。
