White D M, McMahon L J, Denny W F
Am J Med Sci. 1982 May-Jun;283(3):114-8. doi: 10.1097/00000441-198205000-00001.
In this study we employed the concept of the outcome audit to assess the "benefit" (in contrast to the number of positive readings) derived from 81 bone, 45 brain, and 47 liver scans, performed on 59 bronchogenic carcinoma patients. Benefit was rigorously defined and based on any outcome instrumental in the subsequent management of the patient. Clinically indicated scans were frequently found to be of benefit, while those without indications were not (88.0% vs. 12.5%). Negative scans were as useful as positive scans if clinically indicated (14.0% vs. 9.6%). Histology did not influence the likelihood of benefit. We conclude that scans obtained to evaluate a clinical abnormality are likely to be useful whether positive or negative while scans ordered without specific clinical indications are unlikely to be of management benefit.
在本研究中,我们运用结果审计的概念,评估了对59例支气管肺癌患者进行的81次骨骼扫描、45次脑部扫描和47次肝脏扫描所产生的“益处”(与阳性读数的数量相对)。益处经过严格定义,基于对患者后续管理有帮助的任何结果。经常发现有临床指征的扫描是有益的,而无指征的扫描则不然(88.0%对12.5%)。如果有临床指征,阴性扫描与阳性扫描一样有用(14.0%对9.6%)。组织学不影响有益的可能性。我们得出结论,为评估临床异常而进行的扫描,无论结果是阳性还是阴性,都可能是有用的,而无特定临床指征时进行的扫描不太可能对管理有帮助。