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结肠浆细胞瘤:免疫过氧化物酶研究证实的λ轻链病例报告

Plasmacytoma of the colon: case report with lambda light chain, demonstrated by immunoperoxidase studies.

作者信息

Gleason T H, Hammar S P

出版信息

Cancer. 1982 Jul 1;50(1):130-3. doi: 10.1002/1097-0142(19820701)50:1<130::aid-cncr2820500124>3.0.co;2-o.

DOI:10.1002/1097-0142(19820701)50:1<130::aid-cncr2820500124>3.0.co;2-o
PMID:6805937
Abstract

A case of solitary extramedullary plasmacytoma in the transverse colon of a 20-year-old woman is reported. This case is unusual in that the plasmacytomas are only rarely observed in the gastrointestinal tract and are especially uncommon in the colon and in young women. The lesion was composed of pleomorphic plasma cells and contained areas of extracellular amyloid deposition. Its neoplastic nature was verified by the use of immunoperoxidase studies which are positive only for lambda light chain. The subject of gastrointestinal plasmacytomas and the use of immunoperoxidase studies on plasmacytic lesions are discussed.

摘要

报告了一例20岁女性横结肠孤立性髓外浆细胞瘤。该病例不同寻常之处在于,浆细胞瘤在胃肠道中极为罕见,在结肠以及年轻女性中尤其少见。病变由多形性浆细胞组成,并含有细胞外淀粉样蛋白沉积区域。通过免疫过氧化物酶研究证实了其肿瘤性质,该研究仅对λ轻链呈阳性。文中讨论了胃肠道浆细胞瘤以及对浆细胞性病变进行免疫过氧化物酶研究的相关内容。

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