单糖对继发性IgG应答的抑制作用：I区控制的证据。
Inhibition of secondary IgG responses by monosaccharides: evidence for I-region control.
作者信息
Tomaska L D, Parish C R
出版信息
J Immunogenet. 1982 Apr;9(2):63-8. doi: 10.1111/j.1744-313x.1982.tb00964.x.
Abstract
Certain monosaccharides selectively inhibit secondary IgG responses in vitro. Genetic analyses described in this report revealed that the inhibitory sugars differed between mouse strains and these differences mapped to the I-J and I-C subregions of the murine MHC. These results imply that interaction between T and B lymphocytes can involve the recognition of I-region controlled carbohydrate structures.
摘要
某些单糖在体外能选择性地抑制继发性IgG反应。本报告中所描述的遗传学分析表明，抑制性糖类在不同小鼠品系间存在差异，且这些差异定位于小鼠主要组织相容性复合体（MHC）的I-J和I-C亚区。这些结果表明，T淋巴细胞与B淋巴细胞之间的相互作用可能涉及对I区所控制的碳水化合物结构的识别。
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