Patten E, Reddi C R, Riglin H, Edwards J
Transfusion. 1982 May-Jun;22(3):248-50. doi: 10.1046/j.1537-2995.1982.22382224953.x.
Delayed hemolytic transfusion reactions usually occur as a result of a secondary immune response with maximal hemolysis occurring seven days posttransfusion. We report a delayed hemolytic transfusion reaction in which hemoglobinuria, anemia, and reticulocytosis developed four weeks after transfusion. The incriminated antibody, anti-C, was first detected eight weeks posttransfusion using enzyme-treated red blood cells. We conclude, that in all likelihood, this hemolytic transfusion reaction was due to a primary immune response, this case illustrates the importance of sequential testing in cases of suspected transfusion reactions.
迟发性溶血性输血反应通常是二次免疫反应的结果，最大溶血发生在输血后七天。我们报告一例迟发性溶血性输血反应，输血四周后出现血红蛋白尿、贫血和网织红细胞增多。致病抗体抗-C首次在输血八周后使用酶处理的红细胞检测到。我们得出结论，很可能这种溶血性输血反应是由于初次免疫反应引起的，该病例说明了在疑似输血反应病例中进行序贯检测的重要性。
