Routes to the formation of N-methyl-4-aminophenol, a metabolite of N,N-dimethylaniline.
作者信息
Gooderham N J, Gorrod J W
出版信息
Adv Exp Med Biol. 1981;136 Pt B:1109-20.
PMID:6807064
Abstract
摘要
相似文献
1
Routes to the formation of N-methyl-4-aminophenol, a metabolite of N,N-dimethylaniline.
Adv Exp Med Biol. 1981;136 Pt B:1109-20.
2
Species and substrate differences of liver microsomal N-dealkylation and N-oxidation of tertiary amines and N-dealkylation of N-oxides.肝脏微粒体中叔胺的N-脱烷基化和N-氧化以及N-氧化物的N-脱烷基化的物种和底物差异。
Xenobiotica. 1971 Jul-Oct;1(4):533-4. doi: 10.3109/00498257109041522.
3
N-oxidation of a tertiary amine (N,N-dimethylaniline) by human fetal liver microsomes.
Clin Pharmacol Ther. 1974 Jan;15(1):32-8. doi: 10.1002/cpt197415132.
4
Studies on drug metabolism. 13. Possible role of liver microsomal cytochrome P-450 in the oxidative N-demethylation of p-substituted dimethylaniline, N-methyl-N-alkylaniline and N-methyl-N-acylaniline derivatives.
Chem Pharm Bull (Tokyo). 1972 Apr;20(4):650-6. doi: 10.1248/cpb.20.650.
5
The N-hydroxylation of phentermine (2-methyl-2-amino-1-phenylpropane). Properties of the enzyme system.
Drug Metab Dispos. 1974 Jan-Feb;2(1):1-8.
6
Studies on the mechanism of hepatic microsomal N-oxide formation. I. Effect of carbon monoxide on the N-oxidation of N,N-dimethylaniline.肝脏微粒体N-氧化形成机制的研究。I. 一氧化碳对N,N-二甲基苯胺N-氧化的影响。
Hoppe Seylers Z Physiol Chem. 1974 Dec;355(12):1508-14. doi: 10.1515/bchm2.1974.355.2.1508.
7
Oxidation and protein binding of aromatic amines by rat liver microsomes.大鼠肝脏微粒体对芳香胺的氧化及蛋白质结合作用。
Chem Biol Interact. 1971 Oct;3(5):321-36. doi: 10.1016/0009-2797(71)90012-3.
8
Evidence for p-hydroxylation of N-ethyl-N-methylaniline.
Xenobiotica. 1980 Jul-Aug;10(7-8):603-10. doi: 10.3109/00498258009033794.
9
Some factors affecting the conversion of pyrrolizidine alkaloids to N-oxides and to pyrrolic derivatives in vitro.一些影响吡咯里西啶生物碱在体外转化为N-氧化物和吡咯衍生物的因素。
Xenobiotica. 1971 Jul-Oct;1(4):503-5. doi: 10.3109/00498257109041518.
10
Teratogen metabolism: thalidomide activation is mediated by cytochrome P-450.
Toxicol Appl Pharmacol. 1986 Jan;82(1):175-9. doi: 10.1016/0041-008x(86)90449-7.
引用本文的文献
1
The in vitro metabolism of N,N-dimethylaniline by guinea pig and rabbit tissue preparations.豚鼠和兔组织制剂对N，N-二甲基苯胺的体外代谢
Eur J Drug Metab Pharmacokinet. 1981;6(3):195-206. doi: 10.1007/BF03189489.
Zotero 插件