多胺生物合成与皮肤肿瘤促进作用：鸟氨酸脱羧酶不可逆抑制剂α-二氟甲基鸟氨酸对12-O-十四烷酰佛波醇-13-乙酸酯促进的小鼠皮肤肿瘤形成的抑制作用 - Suppr

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超能文献

Polyamine biosynthesis and skin tumor promotion: inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase alpha-difluoromethylornithine.

作者信息

Takigawa M, Verma A K, Simsiman R C, Boutwell R K

出版信息

Biochem Biophys Res Commun. 1982 Apr 14;105(3):969-76. doi: 10.1016/0006-291x(82)91065-8.

DOI:10.1016/0006-291x(82)91065-8

PMID:6807316

Abstract

摘要

相似文献

Polyamine biosynthesis and skin tumor promotion: inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase alpha-difluoromethylornithine.多胺生物合成与皮肤肿瘤促进作用：鸟氨酸脱羧酶不可逆抑制剂α-二氟甲基鸟氨酸对12-O-十四烷酰佛波醇-13-乙酸酯促进的小鼠皮肤肿瘤形成的抑制作用

Biochem Biophys Res Commun. 1982 Apr 14;105(3):969-76. doi: 10.1016/0006-291x(82)91065-8.

alpha-Difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits tumor promoter-induced polyamine accumulation and carcinogenesis in mouse skin.α-二氟甲基鸟氨酸是鸟氨酸脱羧酶的不可逆抑制剂，可抑制肿瘤启动子诱导的小鼠皮肤多胺积累和致癌作用。

Proc Natl Acad Sci U S A. 1982 Oct;79(19):6028-32. doi: 10.1073/pnas.79.19.6028.

Inhibition of mouse skin tumor promotion and of promoter-stimulated epidermal polyamine biosynthesis by alpha-difluoromethylornithine.α-二氟甲基鸟氨酸对小鼠皮肤肿瘤促进作用及启动子刺激的表皮多胺生物合成的抑制作用。

Cancer Res. 1983 Aug;43(8):3732-8.

Accumulation of decarboxylated S-adenosyl-L-methionine in mammalian cells as a consequence of the inhibition of putrescine biosynthesis.由于腐胺生物合成受到抑制，哺乳动物细胞中脱羧S-腺苷-L-甲硫氨酸的积累。

Eur J Biochem. 1982 Apr;123(3):499-504. doi: 10.1111/j.1432-1033.1982.tb06559.x.

Vitamin A acid (retinoic acid), a potent inhibitor of 12-O-tetradecanoyl-phorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis.维甲酸（视黄酸），一种对12 - O - 十四烷酰佛波醇 - 13 - 乙酸酯诱导的小鼠表皮鸟氨酸脱羧酶活性有强效抑制作用的物质。

Cancer Res. 1977 Jul;37(7 Pt 1):2196-201.

Effect of inhibitors on ornithine and adenosylmethionine decarboxylases on the synthesis of deoxyribonucleic acid in Ehrlich ascites cells in vivo.鸟氨酸脱羧酶和腺苷甲硫氨酸脱羧酶抑制剂对艾氏腹水癌细胞体内脱氧核糖核酸合成的影响。

Acta Chem Scand B. 1979;33(8):559-66. doi: 10.3891/acta.chem.scand.33b-0559.

Changes in epidermal polyamine biosynthesis and specific activity of DNA following a single application of 12-O-tetradecanoyl-phorbol-13-acetate to hairless mouse skin.单次将12-O-十四烷酰佛波醇-13-乙酸酯涂抹于无毛小鼠皮肤后，表皮多胺生物合成及DNA比活性的变化。

Carcinogenesis. 1981;2(6):545-51. doi: 10.1093/carcin/2.6.545.

Restoration of the polyamine contents in rat hepatoma tissue-culture cells after inhibition of polyamine biosynthesis. Relationship with cell proliferation.多胺生物合成受抑制后大鼠肝癌组织培养细胞中多胺含量的恢复。与细胞增殖的关系。

Eur J Biochem. 1986 Apr 1;156(1):31-5. doi: 10.1111/j.1432-1033.1986.tb09544.x.

Ornithine decarboxylase and polyamines in tissues of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase.新生大鼠组织中的鸟氨酸脱羧酶和多胺：鸟氨酸脱羧酶特异性不可逆抑制剂α-二氟甲基鸟氨酸的作用

J Pharmacol Exp Ther. 1982 Sep;222(3):741-5.

Inhibition of polyamine synthesis and proliferation in mouse L cells by DL-alpha-hydrazino-delta-aminovaleric acid, an inhibitor of ornithine decarboxylase.鸟氨酸脱羧酶抑制剂DL-α-肼基-δ-氨基戊酸对小鼠L细胞多胺合成及增殖的抑制作用

J Biochem. 1983 Jul;94(1):97-106. doi: 10.1093/oxfordjournals.jbchem.a134359.

引用本文的文献

S-adenosylmethionine decarboxylase overexpression inhibits mouse skin tumor promotion.S-腺苷甲硫氨酸脱羧酶过表达抑制小鼠皮肤肿瘤促进作用。

Carcinogenesis. 2012 Jul;33(7):1310-8. doi: 10.1093/carcin/bgs184. Epub 2012 May 19.

Effect of dietary omega-3 and omega-6 fatty acid sources on PUVA-induced cutaneous toxicity and tumorigenesis in the hairless mouse.膳食中ω-3和ω-6脂肪酸来源对无毛小鼠PUVA诱导的皮肤毒性和肿瘤发生的影响。

Arch Dermatol Res. 1994;286(6):331-6. doi: 10.1007/BF00402224.

Active oxygen acts as a promoter of transformation in mouse embryo C3H/10T1/2/C18 fibroblasts.活性氧在小鼠胚胎C3H/10T1/2/C18成纤维细胞中作为转化促进剂起作用。

Proc Natl Acad Sci U S A. 1984 Apr;81(7):2085-7. doi: 10.1073/pnas.81.7.2085.

Biological action of epidermal growth factor and its functional receptors in normal mammary epithelial cells.表皮生长因子及其功能受体在正常乳腺上皮细胞中的生物学作用。

Proc Natl Acad Sci U S A. 1983 May;80(9):2647-50. doi: 10.1073/pnas.80.9.2647.

Tumor promoter 12-O-tetradecanoylphorbol 13-acetate, like epidermal growth factor, stimulates cell proliferation and inhibits differentiation of mouse mammary epithelial cells in culture.肿瘤促进剂十四酰佛波醇乙酸酯（12-O-十四烷酰佛波醇-13-乙酸酯）与表皮生长因子一样，能刺激细胞增殖并抑制培养的小鼠乳腺上皮细胞分化。

Proc Natl Acad Sci U S A. 1983 Mar;80(6):1646-9. doi: 10.1073/pnas.80.6.1646.

Focal smooth muscle proliferation in the aortic intima produced by an initiation-promotion sequence.由启动-促进序列产生的主动脉内膜局灶性平滑肌增殖。

Proc Natl Acad Sci U S A. 1985 May;82(10):3450-4. doi: 10.1073/pnas.82.10.3450.

Ornithine decarboxylase from mouse epidermis and epidermal papillomas: differences in enzymatic properties and structure.来自小鼠表皮和表皮乳头瘤的鸟氨酸脱羧酶：酶学性质和结构的差异。

Proc Natl Acad Sci U S A. 1986 Dec;83(24):9448-52. doi: 10.1073/pnas.83.24.9448.

Immunocytochemical localization of ornithine decarboxylase in cultured murine cells.鸟氨酸脱羧酶在培养的鼠细胞中的免疫细胞化学定位

Cell Tissue Res. 1986;243(1):33-40. doi: 10.1007/BF00221849.

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