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光适应大鼠视网膜多巴胺能神经元活动对黑暗的适应性

Adaptation of retinal dopamine neuron activity in light-adapted rats to darkness.

作者信息

Proll M A, Morgan W W

出版信息

Brain Res. 1982 Jun 10;241(2):359-61. doi: 10.1016/0006-8993(82)91078-2.

DOI:10.1016/0006-8993(82)91078-2
PMID:6809228
Abstract

The activity of the retinal dopamine neurons was studied in light-adapted rats exposed to darkness for periods ranging from 10 min to 15 h. Dihydroxyphenylalanine (DOPA) accumulation, following inhibition of L-aromatic amino acid decarboxylase with NSD-1015, was used as an index of dopamine neuronal activity. After only 10 min of darkness, DOPA accumulation had decreased to levels found in rats dark-adapted for 15 h.

摘要

在光照适应的大鼠中,研究了其视网膜多巴胺神经元在暴露于黑暗中10分钟至15小时期间的活动。用NSD - 1015抑制L - 芳香族氨基酸脱羧酶后,二羟基苯丙氨酸(DOPA)的积累被用作多巴胺神经元活动的指标。仅在黑暗10分钟后,DOPA积累就已降至适应黑暗15小时的大鼠中的水平。

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Effect of levodopa on the human dark adaptation threshold.左旋多巴对人体暗适应阈值的影响。
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Tyrosine administration enhances dopamine synthesis and release in light-activated rat retina.
给予酪氨酸可增强光激活大鼠视网膜中的多巴胺合成与释放。
J Neural Transm. 1983;56(2-3):153-60. doi: 10.1007/BF01243274.
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