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脑内血栓形成的动静脉畸形。是难治性局灶性癫痫发作疾病鉴别诊断中的一个重要实体。

Thrombosed arteriovenous malformations of the brain. An important entity in the differential diagnosis of intractable focal seizure disorders.

作者信息

Wharen R E, Scheithauer B W, Laws E R

出版信息

J Neurosurg. 1982 Oct;57(4):520-6. doi: 10.3171/jns.1982.57.4.0520.

DOI:10.3171/jns.1982.57.4.0520
PMID:6809908
Abstract

Thrombosed arteriovenous malformations (AVM's) in patients with no previous history of hemorrhage are uncommon but benign lesions that present with clinical and radiographic findings which are often indistinguishable from those of other mass lesions, particularly low-grade gliomas. The authors report seven cases of thrombosed AVM's presenting as intractable seizure disorders in which the radiographic studies had suggested a low-grade glioma. All seven patients are now seizure-free 2 to 40 months postoperatively. The importance of surgical exploration in the management of such patients is emphasized. A review of 32 cases reported in the literature is presented. The reasons why angiography may fail to demonstrate an AVM, and the possible etiologies for the spontaneous thrombosis of an AVM are discussed.

摘要

既往无出血史的患者发生血栓形成的动静脉畸形(AVM)并不常见,但属于良性病变,其临床和影像学表现常与其他占位性病变难以区分,尤其是低级别胶质瘤。作者报告了7例以难治性癫痫发作障碍为表现的血栓形成的AVM,其影像学检查提示为低级别胶质瘤。所有7例患者术后2至40个月均无癫痫发作。强调了手术探查在此类患者管理中的重要性。本文还对文献报道的32例病例进行了综述。讨论了血管造影可能无法显示AVM的原因以及AVM自发血栓形成的可能病因。

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Thrombosed arteriovenous malformations of the brain. An important entity in the differential diagnosis of intractable focal seizure disorders.脑内血栓形成的动静脉畸形。是难治性局灶性癫痫发作疾病鉴别诊断中的一个重要实体。
J Neurosurg. 1982 Oct;57(4):520-6. doi: 10.3171/jns.1982.57.4.0520.
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引用本文的文献

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Cerebral arteriovenous malformation calcifications: A systematic review, case series, and a proposed classification system.脑动静脉畸形钙化:一项系统评价、病例系列及拟议的分类系统
Surg Neurol Int. 2025 Mar 28;16:104. doi: 10.25259/SNI_102_2025. eCollection 2025.
2
Ruptured Arteriovenous Malformation Anterior to the Brainstem to a Child with Subsequent Spontaneous Thrombosis: Case Report and Literature Review.脑干部前破裂动静脉畸形伴自发性血栓形成:病例报告及文献复习。
Am J Case Rep. 2020 May 1;21:e923289. doi: 10.12659/AJCR.923289.
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Intracranial Gorgon: Surgical Case Report of a Large Calcified Brain Arteriovenous Malformation.
颅内戈尔贡:大型钙化性脑动静脉畸形的手术病例报告。
Am J Case Rep. 2020 Apr 28;21:e922872. doi: 10.12659/AJCR.922872.
4
Spontaneous thrombosis of an arteriovenous malformation.动静脉畸形的自发性血栓形成。
J Neurol Neurosurg Psychiatry. 1994 Nov;57(11):1410-2. doi: 10.1136/jnnp.57.11.1410.
5
Spontaneous disappearance of intracranial arterio-venous malformations.颅内动静脉畸形的自然消失
Acta Neurochir (Wien). 1985;76(1-2):50-7. doi: 10.1007/BF01403829.
6
Focal seizures with reversible hypodensity on the CT scan.
J Neurol Neurosurg Psychiatry. 1985 Feb;48(2):187-8. doi: 10.1136/jnnp.48.2.187.
7
Arteriovenous malformations of the brain in children.
Childs Nerv Syst. 1987;3(1):12-8. doi: 10.1007/BF00707187.
8
Occult cerebral arteriovenous malformations.隐匿性脑动静脉畸形
J Neurol Neurosurg Psychiatry. 1987 Feb;50(2):218-20. doi: 10.1136/jnnp.50.2.218.