Meyer J G, Forst R
J Neurol. 1977 May 13;215(2):127-33.
The acute alcohol withdrawal state (tremulous state), with mainly vegetative symptoms and without evident loss of conciousness or confusion, was evaluated as to functional psychopathological disturbances aiming to present a complete and objective record of the clinical findings and to establish a control of the course and drug treatment. We tried to meet the inherent inability to cooperate by using proven and also new test devices (flicker fusion, simple reaction time on light and tone, reaction on multiple serial stimuli, visual motor coordination, tachistoscopic perception and memory test, test of concentration and sustained performance with simple arithmetical calculation by analogy with the Pauli test) to circumvent the difficulties arising when patients have to answer long questionnaires. The tests enabled a measurement of the disturbances as objective as possible and proved to have a discriminating sensitivity for different functions. The correlations between the results were found to be similar for alcoholics and controls. tthe degree of the established functional cerebral and cerebellar defects which was revealed was more severe than expected in this mild stage of withdrawal.
对主要伴有植物神经症状且无明显意识丧失或意识模糊的急性酒精戒断状态(震颤状态),就功能性精神病理障碍进行评估,旨在呈现完整且客观的临床发现记录,并对病程及药物治疗进行控制。我们试图通过使用经证实的以及新的测试设备(闪烁融合、对光和声音的简单反应时间、对多个连续刺激的反应、视觉运动协调、速示知觉和记忆测试、注意力和持续操作测试,通过类似于保利测试的简单算术计算)来应对患者固有的不合作情况,以规避患者必须回答冗长问卷时出现的困难。这些测试能够尽可能客观地测量这些障碍,并被证明对不同功能具有区分敏感性。发现酒精依赖者和对照组的结果之间的相关性相似。所揭示的既定功能性脑和小脑缺陷程度在这个轻度戒断阶段比预期的更严重。