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对黑腹果蝇中由溴尿苷和甲磺酸乙酯诱导产生的残翅突变体表型回复体的遗传学研究。

Genetic studies of phenotypic revertants of the vestigial mutant in Drosophila melanogaster, induced by bromouridine and ethyl methanesulfonate.

作者信息

Bazin C, Silber J

出版信息

Mutat Res. 1982 Aug;105(1-2):65-72. doi: 10.1016/0165-7992(82)90209-3.

DOI:10.1016/0165-7992(82)90209-3
PMID:6811882
Abstract

Phenotypic revertants of the vestigial mutant in Drosophila melanogaster were induced by ethyl methanesulfonate and bromouridine. Genetic analysis showed that the revertant phenotype was due to suppressor genes in most cases. 3 suppressor genes were located. A mechanism of action of the genes on the vestigial phenotype is postulated.

摘要

甲磺酸乙酯和溴尿苷诱导了黑腹果蝇残翅突变体的表型回复突变体。遗传分析表明,在大多数情况下,回复突变体表型是由抑制基因引起的。定位了3个抑制基因。推测了这些基因对残翅表型的作用机制。

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引用本文的文献

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Suppressors of the vestigial mutant phenotype increase the level of expression of the gene.残翅突变体表型的抑制因子会提高该基因的表达水平。
Dev Growth Differ. 1996 Oct;38(5):557-564. doi: 10.1046/j.1440-169X.1996.t01-4-00012.x.