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Conformational studies of peptide hormones using laser Raman and circular dichroism spectroscopy. A comparative study of oxytocin agonists and antagonists.

作者信息

Hruby V J, Deb K K, Fox J, Bjarnason J, Tu A T

出版信息

J Biol Chem. 1978 Sep 10;253(17):6060-7.

PMID:681339
Abstract
摘要

相似文献

1
Conformational studies of peptide hormones using laser Raman and circular dichroism spectroscopy. A comparative study of oxytocin agonists and antagonists.
J Biol Chem. 1978 Sep 10;253(17):6060-7.
2
Conformational comparisons of oxytocin agonists, partial agonists, and antagonists using laser Raman and circular dichroism spectroscopy. Examination of 1-penicillamine and diastereoisomeric analogues.
J Biol Chem. 1982 May 10;257(9):4916-24.
3
Laser Raman spectroscopy and circular dichroism studies of the peptide hormones mesotocin, vasotocin, lysine vasopressin, and arginine vasopressin. Conformational analysis.
J Biol Chem. 1979 May 10;254(9):3272-8.
4
Examination of structural characteristics of the potent oxytocin antagonists [dPen1,Pen6]-OT and [dPen1,Pen6, 5-tBuPro7]-OT by NMR, Raman, CD spectroscopy and molecular modeling.通过核磁共振(NMR)、拉曼光谱、圆二色光谱(CD)和分子模拟对强效催产素拮抗剂[dPen1,Pen6]-OT和[dPen1,Pen6, 5-tBuPro7]-OT的结构特征进行研究。
J Pept Sci. 2005 Jul;11(7):365-78. doi: 10.1002/psc.637.
5
A Raman spectroscopic investigation of the disulfide conformation in oxytocin and lysine vasopressin.催产素和赖氨酸加压素中二硫键构象的拉曼光谱研究。
Biochemistry. 1977 Oct 4;16(20):4443-9. doi: 10.1021/bi00639a018.
6
Relative conformational rigidity in oxytocin and (1-penicillamine)-oxytocin: a proposal for the relationship of conformational flexibility to peptide hormone agonism and antagonism.催产素和(1-青霉胺)-催产素中的相对构象刚性:关于构象灵活性与肽类激素激动作用和拮抗作用关系的一项提议。
Proc Natl Acad Sci U S A. 1977 Apr;74(4):1373-7. doi: 10.1073/pnas.74.4.1373.
7
Electronic and vibrational optical activity of several peptides related to neurohypophyseal hormones: disulfide group conformation.几种神经垂体激素相关肽的电子和振动旋光活性:二硫键构象。
Biopolymers. 2012 Nov;97(11):923-32. doi: 10.1002/bip.22105.
8
Strategies in the development of peptide antagonists.肽拮抗剂开发策略。
Prog Brain Res. 1992;92:215-24. doi: 10.1016/s0079-6123(08)61177-2.
9
Conformational studies on tocinamide and deaminotocinamide by 220 MHz nuclear magnetic resonance spectroscopy.通过220兆赫核磁共振光谱对托西酰胺和脱氨基托西酰胺进行构象研究。
Proc Natl Acad Sci U S A. 1972 Jun;69(6):1470-4. doi: 10.1073/pnas.69.6.1470.
10
Conformational studies of oxytocin analogues with different ring sizes. I. Circular dichroism.
Biochim Biophys Acta. 1979 May 23;578(1):87-95. doi: 10.1016/0005-2795(79)90116-8.

引用本文的文献

1
Oxytocin solution structure changes upon protonation of the N-terminus in dimethyl sulfoxide.在二甲基亚砜中,催产素溶液结构在N端质子化时会发生变化。
J Biomol NMR. 1993 Nov;3(6):653-73. doi: 10.1007/BF00198370.
2
Determination of beta-turn conformation by laser Raman spectroscopy.通过激光拉曼光谱法测定β-转角构象。
Biophys J. 1981 Dec;36(3):509-17. doi: 10.1016/S0006-3495(81)84749-2.
3
Effects of conformational constraint in 2- and 8-cycloleucine analogues of oxytocin and [1-penicillamine] oxytocin examined by circular dichroism and bioassay.
通过圆二色性和生物测定法研究催产素和[1-青霉胺]催产素的2-和8-环亮氨酸类似物中构象限制的影响。
J Protein Chem. 1990 Feb;9(1):9-15. doi: 10.1007/BF01024978.