A pharmacological comparison of 6,7-dihydroxy-2-dimethylaminotetralin (TL-99) and N-n-propyl-3-(3-hydroxyphenyl)piperidine with (3-PPP) selected dopamine agonists.

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作者信息

Martin G E, Williams M, Haubrich D R

出版信息

J Pharmacol Exp Ther. 1982 Nov;223(2):298-304.

PMID:6813451

Abstract

摘要

相似文献

A pharmacological comparison of 6,7-dihydroxy-2-dimethylaminotetralin (TL-99) and N-n-propyl-3-(3-hydroxyphenyl)piperidine with (3-PPP) selected dopamine agonists.

J Pharmacol Exp Ther. 1982 Nov;223(2):298-304.

Relative selectivity of 6,7-dihydroxy-2-dimethylaminotetralin, N-n-propyl-3-(3-hydroxyphenyl)piperidine, N-n-propylnorapomorphine and pergolide as agonists at striatal dopamine autoreceptors and postsynaptic dopamine receptors.6,7-二羟基-2-二甲基氨基四氢萘、N-正丙基-3-(3-羟基苯基)哌啶、N-正丙基去甲阿扑吗啡和培高利特作为纹状体多巴胺自身受体和突触后多巴胺受体激动剂的相对选择性。

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Pharmacological profiles of the putative dopamine autoreceptor agonists 3-PPP and TL-99.假定的多巴胺自身受体激动剂3-PPP和TL-99的药理学特征。

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Interaction of the putative dopamine autoreceptor agonists 3-PPP and TL-99 with [3H]apomorphine binding sites in rat striatal membranes.

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Further characterization of structural requirements for agonists at the striatal dopamine D-1 receptor. Studies with a series of monohydroxyaminotetralins on dopamine-sensitive adenylate cyclase and a comparison with dopamine receptor binding.

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Different actions of TL-99 and 3-PPP in producing contraversive turning in the 6-OHDA-lesioned rat.

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Postsynaptic dopamine agonist properties of TL-99 are revealed by yohimbine co-treatment.

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N-methyl,N-propargyl-2-aminotetralins:novel dopamine agonists with monoamine oxidase inhibiting properties.N-甲基，N-炔丙基-2-氨基四氢萘：具有单胺氧化酶抑制特性的新型多巴胺激动剂。

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N-0437: a selective D-2 dopamine receptor agonist in in vitro and in vivo models.

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