机电耦合III。通过分析去表皮肌纤维咖啡因诱导的张力瞬变的时间进程来估计肌浆网的钙储存能力。

Electromechanical coupling III. Estimation of the Ca storage capacity of the SR by analysing the time course of caffeine-induced tension transients of skinned muscle fibres.

作者信息

Thieleczek R

出版信息

Z Naturforsch C Biosci. 1982 Jul-Aug;37(7-8):709-11. doi: 10.1515/znc-1982-7-823.

DOI:10.1515/znc-1982-7-823

Abstract

The Ca uptake of the SR of a skinned fibre, which was studied with an indirect method, shows a biphasic time course. A total Ca concentration between 8 and 23 mm was accumulated in the SR by an initial fast process (tau approximately equal to 4.7 s). This Ca-uptake activity of the SR is high enough to bring about relaxation of twitch contraction in vivo. The magnitude of a subsequent slow process (tau approximately equal to 10(3) s) indicates that the total Ca storage capacity of the SR of skeletal muscle is in the order of 60-75 mm.

摘要

用间接方法研究的去表皮肌纤维肌浆网（SR）的钙摄取呈现双相时间进程。通过初始快速过程（时间常数τ约等于4.7秒），肌浆网积累了总浓度在8至23毫摩尔之间的钙。肌浆网的这种钙摄取活性足以在体内引起单收缩的舒张。随后缓慢过程（时间常数τ约等于10³秒）的幅度表明，骨骼肌肌浆网的总钙储存能力约为60 - 75毫摩尔。