Shah A, Klimo P, Worth A
Arch Dermatol. 1982 Nov;118(11):922-4.
A 62-year-old woman had multiple plasmacytomas of the skin with no roentgenographic or bone marrow evidence of multiple myeloma. Serum IgA-lambda level was increased to 1,000 mg/dL (normal range, 90 to 450 mg/dL). The skin lesions regressed completely when the patient was treated with melphalan. She had recurrence of a skin plasmacytoma and lytic bone lesions ten months later and died of bronchopneumonia 11 months after the was first seen. Solitary skin plasmacytomas are rare, and multiple skin plasmacytomas are even rarer. Occasionally, these lesions may precede roentgenographic and bone marrow evidence of multiple myeloma.
一名62岁女性患有皮肤多发性浆细胞瘤，X线和骨髓检查均无多发性骨髓瘤证据。血清IgA-λ水平升至1000mg/dL（正常范围90至450mg/dL）。患者接受美法仑治疗后皮肤病变完全消退。10个月后她出现皮肤浆细胞瘤复发及溶骨性骨病变，并在首次就诊11个月后死于支气管肺炎。孤立性皮肤浆细胞瘤罕见，多发性皮肤浆细胞瘤更为罕见。这些病变偶尔可能先于多发性骨髓瘤的X线和骨髓证据出现。
