Gougerot-Pocidalo M A, Jacquet B, Pocidalo J J
C R Seances Acad Sci III. 1982 May 17;294(18):925-7.
Mice exposed to pure oxygen develop a lethal edematous pulmonary disease. This Note demonstrates, in these Mice, a lymphoid involution with blood lymphopenia and severe decrease in thymic weight and cellularity. The thymus was completely destroyed following 96 hrs. exposure. The possible role of these leucocyte alterations in normobare oxygen toxicity should be considered.
暴露于纯氧环境中的小鼠会患上致命的水肿性肺部疾病。本报告表明，在这些小鼠中，出现了淋巴样退化，伴有血液淋巴细胞减少以及胸腺重量和细胞数量严重下降。暴露96小时后胸腺完全被破坏。应考虑这些白细胞改变在常压纯氧毒性中可能发挥的作用。
