[Depressor effect of normobaric oxygen on the mouse lymphoid system].

Mice exposed to pure oxygen develop a lethal edematous pulmonary disease. This Note demonstrates, in these Mice, a lymphoid involution with blood lymphopenia and severe decrease in thymic weight and cellularity. The thymus was completely destroyed following 96 hrs. exposure. The possible role of these leucocyte alterations in normobare oxygen toxicity should be considered.