Dobracheva A D, Zelenetskaia V S, Pishchulin A A
Probl Endokrinol (Mosk). 1982 Sep-Oct;28(5):33-7.
As a result of the study of the LH, FSH, prolactin and testosterone content in the blood of patients with androgen-producing ovarian tumors and LH-tumor tissue binding in vitro, it was detected that the gonadotropic hormone content may be low, normal and high. The testosterone level does not correlate with LH, FSH and prolactin concentration. LH-receptor binding is disturbed in the androgen-producing tumor tissue and hormone presence is not necessary to maintain androgen secretion by the tumor.
通过对产生雄激素的卵巢肿瘤患者血液中的促黄体生成素(LH)、促卵泡生成素(FSH)、催乳素和睾酮含量以及LH与肿瘤组织的体外结合情况进行研究,发现促性腺激素含量可能偏低、正常或偏高。睾酮水平与LH、FSH和催乳素浓度无关。在产生雄激素的肿瘤组织中,LH受体结合受到干扰,且肿瘤维持雄激素分泌并不一定需要激素的存在。