Juron-Dupraz F, Betuel H, Jouvenceaux A
Rev Fr Transfus Immunohematol. 1982 Sep;25(4):439-50. doi: 10.1016/s0338-4535(82)80033-0.
From 1955 through 1978, 150 immunohemolytic accidents of variable gravity have been documented, representing an incidence of 7.1 cases out of 100 000 transfused blood units. These accidents can be classified as follows: 83 cases due to ABO incompatibility, 42 cases due to an irregular antibody in the recipient (six times due to anti-D), 20 cases induced by passive maternal antibodies in the newborn and 5 cases which were attributed to injected anti-A or anti-B antibodies. Ten deaths were recorded, all ascribed to ABO (8 cases) and to Rhesus D (2 cases) incompatibilities. In the present study, a major decrease in the incidence of ABO accidents has been observed, especially since 1966 with systematic controls being performed at the patient's bedside. However, irregular antibodies were the cause of the conflicts in only 10% of the cases when the study was started, and is now incriminated in 8 cases out of 10.
从1955年到1978年，共记录了150起不同严重程度的免疫性溶血事故，相当于每10万个输血单位中有7.1例发病。这些事故可分类如下：83例由ABO血型不相容引起，42例由受血者体内不规则抗体引起（其中6例由抗-D抗体引起），20例由新生儿体内被动获得的母体抗体引起，5例由注射抗-A或抗-B抗体引起。记录到10例死亡，均归因于ABO血型不相容（8例）和RhD血型不相容（2例）。在本研究中，观察到ABO血型事故的发生率大幅下降，特别是自1966年以来，在患者床边进行了系统检查。然而，在研究开始时，不规则抗体仅在10%的病例中导致血型冲突，而现在每10例中有8例与之有关。
