Scott G B
Vet Pathol Suppl. 1982 Sep;7:134-40.
Microhernias of colonic mucosal glands through the muscularis mucosae are common in human and nonhuman primate colons, and are related to submucosal lymphoid nodules. In nonhuman primates they have been shown to play an important role in the spread of inflammatory diseases from the lamina propria to the submucosa by allowing the infective agents to pass through the muscularis mucosae. The lymphoid tissue of the alimentary tract is composed predominantly of B lymphocytes and produces humoral antibodies. This property of the lymphoid component of these microhernias may thus play a significant role in determining which infective colonic diseases penetrate into the submucosa and which remain largely confined to the lamina propria.
结肠黏膜腺通过黏膜肌层形成的微小疝在人类和非人灵长类动物的结肠中很常见，且与黏膜下淋巴小结有关。在非人灵长类动物中，已表明它们通过使感染因子穿过黏膜肌层，在炎症性疾病从固有层扩散到黏膜下层的过程中发挥重要作用。消化道的淋巴组织主要由B淋巴细胞组成，并产生体液抗体。因此，这些微小疝的淋巴成分的这一特性可能在决定哪些感染性结肠疾病会穿透到黏膜下层以及哪些疾病主要局限于固有层方面发挥重要作用。
