Zupańska B, Maślanka K, van Loghem E
Vox Sang. 1982 Nov;43(5):243-7. doi: 10.1111/j.1423-0410.1982.tb00019.x.
13 anti-Rh sera were compared for their usefulness in the detection of Fc-receptor-bearing lymphocytes (EAhum test). IgG subclasses of anti-Rh antibodies were determined by the antiglobulin test with monospecific sera and by the detection of Gm allotypic markers in the haemagglutination inhibition test. Six sera with IgG1 + IgG3 or IgG1 + IgG2 + IgG3 antibodies and one with pure IgG3 antibodies were found to be useful, whereas six other sera with only IgG1 were unsuitable for the EAhum test. G3m markers were detected only on the anti-Rh antibodies which were capable of forming rosettes with lymphocytes. The data show that human peripheral lymphocytes possess Fc receptors for IgG3 immunoglobulins.
比较了13种抗Rh血清在检测携带Fc受体的淋巴细胞（EAhum试验）中的效用。通过用单特异性血清进行抗球蛋白试验以及在血凝抑制试验中检测Gm同种异型标记来确定抗Rh抗体的IgG亚类。发现6种含有IgG1 + IgG3或IgG1 + IgG2 + IgG3抗体的血清以及1种含有纯IgG3抗体的血清是有用的，而另外6种仅含有IgG1的血清不适用于EAhum试验。仅在能够与淋巴细胞形成花环的抗Rh抗体上检测到G3m标记。数据表明，人外周淋巴细胞具有针对IgG3免疫球蛋白的Fc受体。
