Garcia-Segura L M, Rodriguez-Gonzalez C, Gonzalez-Ros J M
J Hirnforsch. 1978;19(1):75-83.
This study deals with the effects that are produced by an enriched early experience on the mitochondrial fraction on the mice brain. The total content of lipids and proteins in mitochondrial fraction, the morphology of the mitochondries and the density of synaptosomes were investigated. A significant difference in the total quantity of lipids of the mitochondrial fraction and the density of synaptosomes was observed between mice subjected to an enriched environment and others subjected to an impoverished environment. These mice, which were subjected to a psychological study before proceeding to the extraction of the mitochondrial fraction, displayed distinct characteristics. The enriched group displayed a greater exploratory behaviour and a greater capacity to learn than the mice raised in the impoverished environment.
本研究探讨了丰富的早期经历对小鼠大脑线粒体部分产生的影响。研究了线粒体部分中脂质和蛋白质的总含量、线粒体的形态以及突触体的密度。在处于丰富环境的小鼠和处于贫瘠环境的小鼠之间，观察到线粒体部分脂质总量和突触体密度存在显著差异。这些在提取线粒体部分之前接受过心理学研究的小鼠表现出明显的特征。与在贫瘠环境中饲养的小鼠相比，丰富环境组表现出更强的探索行为和学习能力。
