Leslie N T, Harris J R, Hellman S
Breast Cancer Res Treat. 1982;2(3):213-20. doi: 10.1007/BF01806933.
Primary radiation therapy, usually with limited surgery, is being used increasingly as an alternative to mastectomy in patients with early breast cancer. Results so far appear similar in terms of local control and overall survival. Current questions on patient selection, extent of surgery, radiation therapy technique, possible long-term complications, and the role of axillary dissection and of adjuvant therapy are reviewed. Though many questions remain, it is hoped that this alternative will contribute to improved survival along with breast preservation for improved quality of life.
对于早期乳腺癌患者，主要采用放射治疗，通常辅以有限的手术，作为乳房切除术的替代方案，其应用越来越广泛。就局部控制和总生存率而言，目前的结果似乎相似。本文综述了目前在患者选择、手术范围、放射治疗技术、可能的长期并发症以及腋窝清扫和辅助治疗的作用等方面存在的问题。尽管仍有许多问题有待解决，但希望这种替代方案能在提高生存率的同时，保留乳房，改善生活质量。
