小鼠耳部肿瘤生长的定量分析。
Quantitation of tumor growth in the ears of mice.
作者信息
Maia L C, Guerra R N, Rossi M I
出版信息
J Immunol Methods. 1982 Nov 26;55(1):135-9. doi: 10.1016/0022-1759(82)90086-2.
PMID:6818280
Abstract
Transplantation of ascitic P-815 mastocytoma cells intradermally in the ears of syngeneic DBA/2J mice allows a simple and precise quantitation of tumor growth by ear swelling. Tumor growth was retarded and then arrested in allogeneic DBA/1J mice, whereas syngeneic hosts died as a result of tumor dissemination in draining lymph nodes, liver and spleen.
摘要
将腹水型P - 815肥大细胞瘤细胞皮内移植到同基因DBA/2J小鼠的耳部，可通过耳部肿胀对肿瘤生长进行简单而精确的定量。在异基因DBA/1J小鼠中，肿瘤生长受到抑制，然后停止，而异基因宿主则因肿瘤在引流淋巴结、肝脏和脾脏中扩散而死亡。
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