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[硝酸甘油对心肌梗死周边区域各种酶活性的影响]

[Effect of nitroglycerin on various enzyme activity in the peri-infarction area of the myocardium].

作者信息

Cherpachenko N M, Afonskaia N I, Ostrogorskiĭ Iu M, Vikhert A M, Ruda M Ia

出版信息

Kardiologiia. 1982 Nov;22(11):49-53.

PMID:6818399
Abstract

A histochemical study of the activity of some enzymes in the peri-infarction area of rabbit myocardium in response to nitroglycerin showed the latter to increase the activity of oxydative-reductive enzymes in heart tissue, reduce acidosis, intensify the pentosephosphate cycle and contribute to a more intensive resorption of necrotized muscular fibres. These effects are conducive to better cardiomyocytes survival in the peri-infarction area and a more intensive organization of the infarction, this reducing the size of the affected area.

摘要

一项关于兔心肌梗死周边区域某些酶活性对硝酸甘油反应的组织化学研究表明,硝酸甘油可增加心脏组织中氧化还原酶的活性,减轻酸中毒,强化磷酸戊糖循环,并有助于更强烈地吸收坏死的肌纤维。这些作用有助于梗死周边区域更好地存活心肌细胞,并更强烈地促进梗死组织化,从而减小受影响区域的大小。

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