Ganzenko V P, Sumarokov A A, Nikonova V A, Filipov Iu V, Valcarcel Novo M
Zh Mikrobiol Epidemiol Immunobiol. 1982 Dec(12):44-54.
The investigation was carried out to study the safety and reactogenicity of meningococcal chemical polyvalent (ABC) vaccine with the aim of finding the optimum vaccination doses of this vaccine for the immunization of children of different age groups. The investigation, carried out in accordance with the methodological principles of a strictly controlled epidemiological field trial, showed the preparation to be safe, nonreactogenic and to produce no pronounced sensitizing effect.
开展该调查是为了研究脑膜炎球菌化学多价(ABC)疫苗的安全性和反应原性,目的是找到该疫苗用于不同年龄组儿童免疫的最佳接种剂量。按照严格对照的流行病学现场试验的方法学原则进行的调查表明,该制剂安全、无反应原性且不会产生明显的致敏作用。