Ravault J P, Barenton B, Blanc M, Daveau A, Garnier D H, Ortavant R, Pelletier J, de Reviers M M, Terqui M
Reprod Nutr Dev (1980). 1982;22(6):989-98. doi: 10.1051/rnd:19820710.
The influence of 2-Br-alpha-ergocryptine (CB 154) on the secretion of gonadotrophins and on testicular function has been studied in rams subjected to either a normal photoperiod or an abnormal photoperiod causing hyperprolactinaemia. The CB 154 treatment significantly lowered the mean frequency of LH and testosterone pulses in hyperprolactinaemic animals as compared to solvent-treated ones. Also, only those groups subjected to an abnormal photoperiod (groups 2 and 3) exhibited a significant rise in the frequency of LH and testosterone peaks after CB 154 was withdrawn. During treatment, plasma FSH concentrations increased significantly only in group 1 which was subjected to normal photoperiodic variations. Testicular growth was delayed in CB 154-treated rams compared to solvent-treated ones only in group 3 (hyperprolactinaemic).
在处于正常光照周期或导致高催乳素血症的异常光照周期的公羊中，研究了2-溴-α-麦角隐亭（CB 154）对促性腺激素分泌和睾丸功能的影响。与溶剂处理的动物相比，CB 154处理显著降低了高催乳素血症动物中LH和睾酮脉冲的平均频率。此外，只有那些处于异常光照周期的组（第2组和第3组）在停用CB 154后，LH和睾酮峰值频率出现显著升高。在治疗期间，仅在经历正常光照周期变化的第1组中，血浆FSH浓度显著增加。与溶剂处理的公羊相比，仅在第3组（高催乳素血症组）中，CB 154处理的公羊睾丸生长延迟。
