Yamada S, Takeda T, Matsumoto K
Cancer. 1983 Jan 1;51(1):136-40. doi: 10.1002/1097-0142(19830101)51:1<136::aid-cncr2820510127>3.0.co;2-x.
A total of 289 cases with malignant pleuroperitoneal effusions were reviewed, and their prognosis were analyzed in relation to the following factors: (1) chronologically divided series; (2) previous tumorectomy of the primary lesion; (3) presence or absence of other metastases; (4) site of effusion; (5) site of the primary lesion; (6) cytologic characteristics of effusion. Prognostic difference among each chronologically divided series was not noticed. Previous tumorectomy slightly improved the patient's survival. Other distant metastases had no significant influence on the prognosis. Pleural effusion gave better prognosis than peritoneal effusion. Patients of breast and lung cancer had longer expectancies, contrasting with those of gastric cancer. Formation of large clusters of cancer cells on smear preparations obtained from the tapped effusions was interpreted as a sign of good prognosis. Frequencies of cancer cell and lymphocyte occurrence on smear preparation did not have any relationship with the prognosis. The results showed that some factors of the patients at malignant effusion accumulating stage did contribute a great deal to their prognosis.
共回顾了289例恶性胸膜腔和腹腔积液病例，并分析了其预后与以下因素的关系：（1）按时间顺序划分的系列；（2）原发灶先前的肿瘤切除术；（3）是否存在其他转移；（4）积液部位；（5）原发灶部位；（6）积液的细胞学特征。未发现各按时间顺序划分的系列之间存在预后差异。先前的肿瘤切除术略微改善了患者的生存率。其他远处转移对预后无显著影响。胸腔积液的预后优于腹腔积液。乳腺癌和肺癌患者的预期生存期较长，与胃癌患者形成对比。从抽取的积液中获得的涂片标本上癌细胞形成大团块被解释为预后良好的迹象。涂片标本上癌细胞和淋巴细胞出现的频率与预后无关。结果表明，恶性积液积聚阶段患者的一些因素对其预后有很大影响。
