Hanks G E, Kinzie J J, White R L, Herring D F, Kramer S
Cancer. 1983 Feb 15;51(4):569-73. doi: 10.1002/1097-0142(19830215)51:4<569::aid-cncr2820510402>3.0.co;2-0.
The outcome of treatment for Hodgkin's disease has been determined for 407 patients treated in 1973. A two-level random sampling assures that these results are representative of the national practice. Actuarial analysis of recurrence-free survival at four years is: Stage IA, 80%; Stage IIA, 75%; Stage IIIA, 60%; combined Stages IB, IIB, and IIIB, 50%. Factors significantly associated with recurrence include stage, histology, age, chemotherapy, new patient load, part-time practice, treatment technique, treatment machine, treatment simulation, work up score, treatment score, and facility of treatment. Major treatment complications by stage ranged from 4-12%; complications are significantly associated with disease location, patient age, and the presence of coexisting disease.
已确定1973年接受治疗的407例霍奇金病患者的治疗结果。两级随机抽样确保这些结果代表全国的治疗情况。四年无复发生存率的精算分析结果为:IA期,80%;IIA期,75%;IIIA期,60%;IB、IIB和IIIB期合并,50%。与复发显著相关的因素包括分期、组织学、年龄、化疗、新患者数量、兼职工作、治疗技术、治疗设备、治疗模拟、检查评分、治疗评分和治疗机构。各期主要治疗并发症发生率在4%至12%之间;并发症与疾病部位、患者年龄和并存疾病的存在显著相关。