Belal A, Ylikoski J
J Laryngol Otol. 1983 Jan;97(1):1-10. doi: 10.1017/s0022215100093737.
Five human temporal bones and three surgical VIIIth nerve biopsies from patients who had previously undergone labyrinthectomy, five months to ten years before examination, were studied by light and electron microscopy. Post-labyrinthectomy dizziness could be explained on the bases of inadequate surgical removal of the vestibular sense-organs, neuroma formation in the vestibule, and high regenerative potential of the vestibular nerve. Post-labyrinthectomy pressure sensation and tinnitus are most probably due to cochlear endolymphatic hydrops and need cochlear neurectomy. The severe atrophy in the sensorineural structures of the cochlea was not associated with retrograde degeneration of the cochlear nerve central axons. This may be of significance in the artificial electrical stimulation of the cochlear nerve in deaf patients.
对5例人类颞骨以及3例曾在检查前5个月至10年接受过迷路切除术患者的手术第八脑神经活检组织进行了光镜和电镜研究。迷路切除术后头晕可基于前庭感觉器官手术切除不充分、前庭内神经瘤形成以及前庭神经的高再生潜力来解释。迷路切除术后的压力感和耳鸣很可能是由于耳蜗内淋巴积水,需要进行耳蜗神经切除术。耳蜗感觉神经结构的严重萎缩与耳蜗神经中枢轴突的逆行性变性无关。这对于聋患者耳蜗神经的人工电刺激可能具有重要意义。