O'Toole C M, Povey S, Hepburn P, Franks L M
Nature. 1983 Feb 3;301(5899):429-30. doi: 10.1038/301429a0.
Recent reports on transfection of mouse cells with DNA from the established human urinary bladder cancer cell lines T24, J82 and EJ (MGH-U1), and the presence of an identical genetic modification in T24 and EJ cells have led us to examine the identity of these and other cultures of urothelial origin. By the criteria of HLA-A-B-C typing 7 and isozyme analysis, we conclude that EJ (MGH-U1) and some cultures of J82 are in fact T24 cells. However, five other bladder cancer cell lines, J82 (CO'T), RT4, RT112, TCCSuP and SCaBER, are clearly distinct from T24 by HLA typing (ref. 7) and/or isozyme patterns.
最近有报告称，用已建立的人膀胱癌细胞系T24、J82和EJ（MGH-U1）的DNA转染小鼠细胞，且T24和EJ细胞存在相同的基因修饰，这促使我们去研究这些以及其他尿路上皮来源培养物的身份。根据HLA-A-B-C分型7标准和同工酶分析，我们得出结论，EJ（MGH-U1）和一些J82培养物实际上是T细胞。然而，其他五个膀胱癌细胞系，J82（CO'T）、RT4、RT112、TCCSuP和SCaBER，通过HLA分型（参考文献7）和/或同工酶模式与T24明显不同。
