Dysgerminoma and serum lactic dehydrogenase levels.

In this study, the author reports the levels of serum lactic dehydrogenase in patients with ovarian dysgerminoma. The results of previous studies have shown that serum lactic dehydrogenase is elevated in patients with primary ovarian carcinoma but not in those with other pelvic tumors, benign or malignant. In the present study, serum lactic dehydrogenase levels were highly elevated before patients were treated for ovarian dysgerminoma and sharply reduced to normal levels after treatment. This finding may demonstrate an important tumor marker in the diagnosis and treatment of ovarian dysgerminoma.