Nicar M J, Skurla C, Sakhaee K, Pak C Y
Urology. 1983 Jan;21(1):8-14. doi: 10.1016/0090-4295(83)90113-9.
The urinary citrate excretion was examined in patients with nephrolithiasis who were categorized on the basis of different physiologic or metabolic abnormalities. A wide prevalence of low citrate excretion (hypocitraturia) was observed, with over one half of our patients with stones exhibiting it. Hypocitraturia was found in all patient categories except primary hyperparathyroidism and hyperuricosuric calcium oxalate nephrolithiasis. As expected, hypocitraturia was present in renal tubular acidosis and in enteric hyperoxaluria. However, urinary citrate was also low in absorptive and renal hypercalciurias, and in patients in whom an acid-base disturbance was clearly excluded.
对患有肾结石的患者进行了尿枸橼酸盐排泄检查，这些患者根据不同的生理或代谢异常进行了分类。观察到低枸橼酸盐排泄（低枸橼酸尿症）的广泛存在，我们超过一半的结石患者表现出这种情况。除原发性甲状旁腺功能亢进和高尿酸尿性草酸钙肾结石外，在所有患者类别中均发现低枸橼酸尿症。正如预期的那样，肾小管酸中毒和肠道高草酸尿症患者存在低枸橼酸尿症。然而，在吸收性和肾性高钙尿症患者以及明确排除酸碱紊乱的患者中，尿枸橼酸盐也较低。
