Grinevich Iu A, Dziubko N Ia, Kokhanevich E V, Vinnitskaia V B, Klevetenko M P
Vopr Onkol. 1983;29(1):43-8.
The study is concerned with immunologic status (cell-mediated and humoral immunity) as a factor influencing the choice of scheme of treatment for carcinoma of cervix uteri. The indexes of immunocompetence should be taken into account in planning the differential treatment of precancer and early forms of carcinoma of cervix uteri. Radiation treatment exerts an immunosuppressive effect. However, immunologic indexes are not affected considerably by laser destruction or surgery. Cryodestruction has a beneficial effect on cell-mediated immunity. Considering these effects as well as the long-term results of different procedures of treatment, laser coagulation, cryogenic destruction or diathermoconization should be recommended for management of carcinoma in situ of cervix uteri, and extensive extirpation of the uterus, unattended by radiation, for Tla.
该研究关注免疫状态(细胞介导免疫和体液免疫)作为影响子宫颈癌治疗方案选择的一个因素。在规划子宫颈癌癌前病变和早期癌的鉴别治疗时,应考虑免疫能力指标。放射治疗具有免疫抑制作用。然而,激光破坏或手术对免疫指标影响不大。冷冻破坏对细胞介导免疫有有益作用。考虑到这些作用以及不同治疗方法的长期结果,对于子宫颈原位癌,建议采用激光凝固、冷冻破坏或透热凝固治疗,对于Tla期,建议在不进行放疗的情况下广泛切除子宫。