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[食管癌的治疗方法及其潜在转移的特别参考]

[Therapeutic approach in cancer of the esophagus with special reference to its potential metastasis].

作者信息

Pirogov A I, Ryndin V D

出版信息

Vopr Onkol. 1983;29(1):6-11.

PMID:6823758
Abstract

A long-term experience with dissemination of tumor of different parts of the esophagus was evaluated using the results of resected material examination and post-operative follow-up. Schemes of treatment for different degree of metastatic spread of esophageal cancer are discussed. Diagnostic laparatomy is recommended prior to surgery, radiation or combination treatment of tumor of the median or lower thirds of the esophagus; laparatomy should remove paracardial lymph nodes, nodes of the lesser omentum as well as retroperitoneal nodes located along the left gastric artery, those in the vicinity of the bifurcation of gastric artery and along the upper boundary of the pancreas. If retroperitoneal lymph nodes are involved, resection of the esophagus is useless and radiation treatment may be recommended as palliation only. Cases of metastases in paracardial lymph nodes or those of the lesser omentum should be provisionally referred to a group of candidates for surgery, while the actual expediency of surgical, radiation or combined treatment of such cases is subject to further evaluation, as more data accumulate. In cases of cancer of the lower third of the esophagus, revision and surgery (radiation) should be carried out in the mediastinal lymph nodes located along the esophagus up to the bifurcation of the trachea; when the median third is involved--along the entire thoracic part of the esophagus; in cases of cancer of the upper third--along the esophagus up to the bifurcation of the trachea, including the cervicosubclavicular lymph nodes.

摘要

利用切除标本检查结果及术后随访情况,对不同部位食管癌的长期扩散经验进行了评估。讨论了针对不同程度食管癌转移扩散的治疗方案。对于食管中下段肿瘤,建议在手术、放疗或综合治疗前进行诊断性剖腹探查;剖腹探查应切除贲门旁淋巴结、小网膜淋巴结以及沿胃左动脉分布的腹膜后淋巴结、胃动脉分叉附近的淋巴结和胰腺上缘的淋巴结。如果腹膜后淋巴结受累,食管切除将毫无意义,此时仅建议采用姑息性放疗。贲门旁淋巴结或小网膜淋巴结转移的病例应暂时归为手术候选组,随着更多数据的积累,此类病例手术、放疗或综合治疗的实际可行性有待进一步评估。对于食管下段癌,应在沿食管直至气管分叉处的纵隔淋巴结进行清扫并手术(放疗);若病变累及中段,则应清扫整个胸段食管周围的淋巴结;对于食管上段癌,应清扫沿食管直至气管分叉处的淋巴结,包括颈锁骨下淋巴结。

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