Reinhardt R A, Tussing G J, Kalkwarf K L
Am Fam Physician. 1983 Jan;27(1):129-34.
Since periodontal disease provides a portal of entry for oral microorganisms during such common events as toothbrushing and mastication, treatment must resolve the inflammatory response if the teeth are to be maintained safely in patients at risk of infectious endocarditis. Prophylactic antibiotics should be administered during periodontal treatment such as debridement of the periodontal pocket and surgical repair of anatomic defects, as well as during oral hygiene training. If optimal periodontal health is achieved and maintained, the risk of systemic bacteremia is minimal.
由于在刷牙和咀嚼等常见活动中，牙周病为口腔微生物提供了一个进入途径，因此，如果要在有感染性心内膜炎风险的患者中安全地保留牙齿，治疗必须消除炎症反应。在进行牙周袋清创术和解剖缺陷的手术修复等牙周治疗期间，以及在口腔卫生训练期间，都应给予预防性抗生素。如果能实现并维持最佳的牙周健康，全身菌血症的风险就会降至最低。
