Marshall V R, Ryall R L, Austin M L, Sinclair G R
Br J Urol. 1983 Feb;55(1):28-33. doi: 10.1111/j.1464-410x.1983.tb07074.x.
The initial slope of the curve relating peak urinary flow rate to voided volume was found to predict an individual's flow rate at bladder volumes of 200 ml or more in normal subjects and those with symptoms of outflow obstruction. The numerical value of this initial slope was found to decline in a hyperbolic fashion with increasing age. A similar decrease was observed for peak urinary flow rates at bladder volumes between 200 and 300 ml. The use of initial slope as an index of voiding ability would appear to be just as effective in discriminating between normal and obstructed men as a single flow rate determination at a large volume and would be of most benefit in those patients unable to void large volumes of urine.
研究发现，在正常受试者以及有排尿梗阻症状的人群中，尿流率峰值与排尿量关系曲线的初始斜率能够预测膀胱容量达到200毫升及以上时个体的尿流率。随着年龄增长，该初始斜率的数值呈双曲线形式下降。在膀胱容量为200至300毫升之间时，尿流率峰值也出现了类似的下降。将初始斜率用作排尿能力指标，在区分正常男性和梗阻男性方面似乎与在大膀胱容量下进行单次尿流率测定同样有效，对于那些无法排出大量尿液的患者最为有益。
